Billions flow into medical research, but not all solutions come from pharmaceutical laboratories. Lowering cholesterol is big business, but it can also be easier! Ubiquinol – the active form of coenzyme Q10 – is one of the strongest fat-soluble antioxidants and can lower LDL cholesterol.
Energy Production and Cell Protection
Ubiquinol – the activated form of coenzyme Q10 – is now well known, as one of the strongest, fat-soluble antioxidants in the organism. Ubiquinol is involved in energy production in the mitochondria and in cell protection. This results in interesting applications, for example for young skin or gum inflammation.
Thus it has a decisive function for heart health in the sense of a stable energy balance in the heart muscle. Regular cell function is not possible without ubiquinol. This results in the sensible additional medication for cardiac insufficiency, high blood pressure, the avoidance of muscle diseases under fat-lowering pharmacotherapy (statins) and other more. An important basic principle is the antioxidative and thus anti-inflammatory effect.
This widespread treatment with statins is particularly associated with problematic side effects.
Why Arteriosclerosis?
Every arteriosclerosis is based on a clearly structured process. With elevated LDL blood levels, cholesterol from the blood can accumulate more in the vascular walls of the arteries. The “bad” LDL cholesterol (Low Density Lipoprotein) is a fat-protein compound that binds fat-soluble substances. Together with the “good” HDL cholesterol (High Density Lipoprotein) it results in the total cholesterol value.
In addition, white blood cells follow the LDL cholesterol into the vessel wall. As a result, the vessel wall thickens, forming inflammatory deposits that reduce the elasticity of the vessels.
This leads to vessel constriction and flow reduction with subsequent circulatory disturbance. An essential factor of this event is the fact that the entire process is accompanied by local inflammation. In particularly unfavourable metabolic conditions, sub-clinical (invisible) whole-body inflammation is suspected.
Why Ubiquinol?
Ubiquinol is an essential prerequisite for a healthy cell metabolism. It has an irreplaceable role in the energy production of the energy power plants (mitochondria) of the cells. The basis of the reference studies was the recognition that ubiquinol can affect very small LDL fragments of only 20 nm in size. Important in this context: Only ubiquinol, the reduced form of the coenzyme Q10, can do this.
After only 2 weeks of ubiquinol treatment, LDL cholesterol decreased by 12.7%.
Positive Study Results
Two German universities in Kiel and Herdecke administered 150 mg daily to 53 healthy volunteers. After only 2 weeks, this not only led to an almost 5-fold increase in CoQ10 plasma levels, but also to a 12.7 % reduction in LDL cholesterol levels.
Oxidized LDL, HDL, total cholesterol and triglyceride levels remained unaffected. It was interesting to look into the details, because a special analysis method showed that the LDL reduction affected particularly dangerous – i.e. atherogenic – particles, which are particularly small at around 20 nm.
As far as the mechanism of action is concerned, it is assumed that biological signals that lead to the formation of LDL are reduced. At the same time, biochemical inflammatory signals were also reduced.
